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通过测量细菌ATP快速测定抗生素的最低抑菌浓度(作者译)

[Rapid determination of the minimal inhibitory concentration of an antibiotic by measuring bacterial ATP (author's transl)].

作者信息

Fauchère J L, Simonet M, Descamps P, Véron M

出版信息

Ann Microbiol (Paris). 1982 Mar-Apr;133(2):293-9.

PMID:7044219
Abstract

The minimal inhibitory concentrations (MIC) of gentamicin for ten strains of Enterobacteriaceae were determined by measuring the bacterial ATP (adenosine triphosphate). ATP was measured by chemiluminescence on 4-h growth cultures which included gentamicin. The MIC results obtained by this method were equivalent to those found with the technique of dilution in liquid medium.

摘要

通过测量细菌的三磷酸腺苷(ATP)来确定庆大霉素对十株肠杆菌科细菌的最低抑菌浓度(MIC)。ATP是通过化学发光法对含有庆大霉素的4小时生长培养物进行测量的。用这种方法获得的MIC结果与在液体培养基中稀释技术所得到的结果相当。

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