对某些β-内酰胺化合物具有抗性的大肠杆菌突变体缺乏外膜孔蛋白F（ompF）。
Mutants of Escherichia coli that are resistant to certain beta-lactam compounds lack the ompF porin.
作者信息
Harder K J, Nikaido H, Matsuhashi M
出版信息
Antimicrob Agents Chemother. 1981 Oct;20(4):549-52. doi: 10.1128/AAC.20.4.549.
Abstract
Carbenicillin-resistant mutants of Escherichia coli K-12 and B/r were found to produce greatly diminished levels of the porin coded by the ompF gene. Physiological and ecological implications of these findings are discussed.
摘要
已发现大肠杆菌K-12和B/r的羧苄青霉素抗性突变体产生由ompF基因编码的孔蛋白水平大幅降低。讨论了这些发现的生理学和生态学意义。
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