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衣原体属中基础生物学与致病潜力的关系。

The relation of basic biology to pathogenic potential in the genus Chlamydia.

作者信息

Moulder J W

出版信息

Infection. 1982;10 Suppl 1:S10-8. doi: 10.1007/BF01640709.

DOI:10.1007/BF01640709
PMID:7044979
Abstract

Chlamydiae are obligately intracellular procaryotic parasites, and their activities as agents of human disease are determined to a large degree by their intracellular way of life. The inside of a host cell is a hostile environment, and few microorganisms survive and multiply intracellularly. Those that do have evolved adaptations that fit them for life inside other cells. Apart from the viruses, chlamydiae are the infectious agents most highly adapted to intracellular life. Of all the properties of chlamydiae, the ones most likely to determine their pathogenic potential are those that reflect their adaptations to life inside host cells. Wherever possible, these chlamydial activities will be indentified and described.

摘要

衣原体是专性细胞内寄生的原核生物寄生虫,它们作为人类疾病病原体的活动在很大程度上取决于其细胞内的生存方式。宿主细胞内部是一个恶劣的环境,很少有微生物能在细胞内生存和繁殖。那些能够在细胞内生存繁殖的微生物已经进化出了适应在其他细胞内生活的特性。除了病毒之外,衣原体是最能适应细胞内生活的感染因子。在衣原体的所有特性中,最有可能决定其致病潜力的是那些反映其对宿主细胞内生活适应的特性。只要有可能,这些衣原体的活动都将被识别和描述。

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本文引用的文献

1
A simplified method for immunological typing of trachoma-inclusion conjunctivitis-lymphogranuloma venereum organisms.一种用于沙眼包涵体结膜炎-性病淋巴肉芽肿生物体免疫分型的简化方法。
Infect Immun. 1973 Mar;7(3):356-60. doi: 10.1128/iai.7.3.356-360.1973.
2
The growth cycle of the psittacosis group of micro-organisms.鹦鹉热微生物群的生长周期。
J Infect Dis. 1959 Sep-Oct;105:129-60. doi: 10.1093/infdis/105.2.129.
3
ELECTRON MICROSCOPIC STUDIES ON THE MODE OF REPRODUCTION OF TRACHOMA VIRUS AND PSITTACOSIS VIRUS IN CELL CULTURES.
Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7189-93. doi: 10.1073/pnas.1102229108. Epub 2011 Apr 11.
4
Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome.基于深度测序的沙眼衣原体转录组发现。
Nucleic Acids Res. 2010 Jan;38(3):868-77. doi: 10.1093/nar/gkp1032. Epub 2009 Nov 18.
5
Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine.沙眼衣原体天然主要外膜蛋白在非人灵长类动物中诱导部分保护作用:对沙眼传播阻断疫苗的启示
J Immunol. 2009 Jun 15;182(12):8063-70. doi: 10.4049/jimmunol.0804375.
6
The essential role of the CopN protein in Chlamydia pneumoniae intracellular growth.CopN蛋白在肺炎衣原体细胞内生长中的重要作用。
Nature. 2008 Nov 6;456(7218):112-5. doi: 10.1038/nature07355. Epub 2008 Oct 1.
7
The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor.沙眼衣原体质粒是染色体基因的转录调节因子和毒力因子。
Infect Immun. 2008 Jun;76(6):2273-83. doi: 10.1128/IAI.00102-08. Epub 2008 Mar 17.
8
Amino acid transport into cultured McCoy cells infected with Chlamydia trachomatis.氨基酸转运至感染沙眼衣原体的培养 McCoy 细胞中。
Infect Immun. 2000 Sep;68(9):5439-42. doi: 10.1128/IAI.68.9.5439-5442.2000.
9
Comparative biology of intracellular parasitism.细胞内寄生的比较生物学
Microbiol Rev. 1985 Sep;49(3):298-337. doi: 10.1128/mr.49.3.298-337.1985.
沙眼病毒和鹦鹉热病毒在细胞培养中繁殖方式的电子显微镜研究
Exp Mol Pathol. 1965 Feb;4:24-39. doi: 10.1016/0014-4800(65)90021-3.
4
ISOLATION OF THE TRACHOMA AGENT IN CELL CULTURE.在细胞培养中分离沙眼病原体。
Proc Soc Exp Biol Med. 1965 Feb;118:354-9. doi: 10.3181/00379727-118-29841.
5
Persistent infection of mouse fibroblasts (McCoy cells) with a trachoma strain of Chlamydia trachomatis.用沙眼衣原体的沙眼菌株持续感染小鼠成纤维细胞( McCoy细胞) 。
Infect Immun. 1981 May;32(2):822-9. doi: 10.1128/iai.32.2.822-829.1981.
6
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Infect Immun. 1980 Dec;30(3):874-83. doi: 10.1128/iai.30.3.874-883.1980.
7
Trachoma agent DNA.
J Mol Biol. 1969 Jun 28;42(3):581-9. doi: 10.1016/0022-2836(69)90245-9.
8
The relation of the psittacosis group (Chlamydiae) to bacteria and viruses.鹦鹉热菌群(衣原体)与细菌和病毒的关系。
Annu Rev Microbiol. 1966;20:107-30. doi: 10.1146/annurev.mi.20.100166.000543.
9
Infection of cell cultures by trachoma agent: enhancement by DEAE-dextran.沙眼病原体对细胞培养物的感染:由二乙氨基乙基葡聚糖增强。
J Infect Dis. 1971 Oct;124(4):419-21. doi: 10.1093/infdis/124.4.419.
10
Estimate of the genome size of various microorganisms.各种微生物基因组大小的估计。
J Bacteriol. 1969 Jun;98(3):1400-1. doi: 10.1128/jb.98.3.1400-1401.1969.