Olsen E G
Postgrad Med J. 1978 Jul;54(633):486-93. doi: 10.1136/pgmj.54.633.486.
Endomyocardial tissue obtained from 237 patients clinically suspected of suffering from congestive cardiomyopathy, has been analysed histologically, histochemically and ultrastructurally. In 51% of patients, the suspected diagnosis was morphologically confirmed and in 24.5%, no pathological evidence of a dilated heart or other pathology was found. The results in these two groups were considered helpful. It is concluded that, even though the morphology of congestive cardiomyopathy in non-specific and the number of other pathology found is small, the continuation of investigation by bioptome is justified. Parameters such as prognosis and length of history can also be assessed. Furthermore, morphological analysis is essential to interpret accurately biochemical and other types of investigations that are being carried out on biopsy material.
对237例临床疑似患有充血性心肌病患者的心肌内膜组织进行了组织学、组织化学和超微结构分析。51%的患者，疑似诊断在形态学上得到证实，24.5%的患者未发现心脏扩张或其他病理改变的病理证据。这两组的结果被认为是有帮助的。得出的结论是，尽管充血性心肌病的形态是非特异性的，且发现的其他病理改变数量较少，但通过活检继续进行研究是合理的。还可以评估诸如预后和病史长度等参数。此外，形态学分析对于准确解释对活检材料进行的生化和其他类型的研究至关重要。
