Kleganov V K
Zh Mikrobiol Epidemiol Immunobiol. 1982 Feb(2):70-3.
Enteropathogenic E. coli (EPEC), among which enterotoxigenic E. coli (ETEC) constituted 90%, were detected in the fecal specimens from 42% of hospitalized patients by means of the bacteriological method and experimental models. 209 out of 479 patients, including 9 cases of yersiniosis, provided 180 findings. All previously known invasive EPEC (12 strains belonging to 7 serovars) and ETEC (76 strains belonging to 20 serovars) isolated in the bacteriological study, were found to be invasive or toxigenic in animal experiments. This indicated that the method of serotyping could be suitable for the diagnosis of escherichiosis in practical laboratories. Suckling mice were used to detect ETEC additionally in 54.7% of patients which increased the total frequency of findings to 43.6%. The isolated bacteria were found to be etiologically lined with diarrheal diseases observed in the patients, which was demonstrated by the results obtained in the determination of their content in the inoculated culture and in the survey of 452 healthy persons (the frequency of isolated from seed material was 2.4%, the frequency of findings on the model was 7%, the total frequency of findings was 5.3%.
通过细菌学方法和实验模型，在42%的住院患者粪便标本中检测到肠致病性大肠杆菌（EPEC），其中产肠毒素大肠杆菌（ETEC）占90%。479名患者中的209名，包括9例耶尔森菌病患者，提供了180项检测结果。在细菌学研究中分离出的所有先前已知的侵袭性EPEC（12株，属于7个血清型）和ETEC（76株，属于20个血清型），在动物实验中均被发现具有侵袭性或产毒性。这表明血清分型方法可能适用于实际实验室中大肠杆菌病的诊断。另外，在54.7%的患者中使用乳鼠检测ETEC，使检测结果的总频率提高到43.6%。所分离的细菌在病因上与患者中观察到的腹泻疾病相关，这在接种培养物中其含量的测定以及对452名健康人的调查结果中得到了证实（从种子材料中分离的频率为2.4%，在模型上检测到的频率为7%，检测结果的总频率为5.3%）。
