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使用FA技术在福尔马林固定材料中检测土拉弗朗西斯菌。一种适用于常规尸检工作的方法。

The use of FA-technique for detecting Francisella tularensis in formalin fixed material. A method useful in routine post mortem work.

作者信息

Mörner T

出版信息

Acta Vet Scand. 1981;22(3-4):296-306. doi: 10.1186/BF03548655.

Abstract

Tularemia is a highly infectious zoonosis, in Sweden usually occurring in the varying hare. The risk of human infections when diagnosing this disease in the laboratory is high. Therefore, a method for diagnosing tularemia in formalin fixed material with the FA-technique has been tested. 46 necropsied varying hares were examined using this method. 28 of the examined animals were diagnosed with tularemia based on conventional post mortem, histological and bacteriological examinations. 96 per cent of them were positive to the FA-technique test. 18 other animals infected with different bacteria and Toxoplasma were also tested. All the controls were negative.

摘要

兔热病是一种高度传染性的人畜共患病,在瑞典通常发生在变色兔身上。在实验室诊断这种疾病时,人类感染的风险很高。因此,已经测试了一种用荧光抗体技术在福尔马林固定材料中诊断兔热病的方法。使用这种方法对46只经尸检的变色兔进行了检查。根据传统的尸检、组织学和细菌学检查,28只被检查的动物被诊断为兔热病。其中96%的动物荧光抗体技术检测呈阳性。还对另外18只感染了不同细菌和弓形虫的动物进行了检测。所有对照均为阴性。

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