• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

色氨酸在治疗广场恐怖症和社交恐惧症患者时会增强氯米帕明的疗效吗？

Does tryptophan potentiate clomipramine in the treatment of agoraphobic and social phobic patients?

作者信息

Pecknold J C, McClure D J, Appeltauer L, Allan T, Wrzesinski L

出版信息

Br J Psychiatry. 1982 May;140:484-90. doi: 10.1192/bjp.140.5.484.

DOI:10.1192/bjp.140.5.484
PMID:7049293
Abstract

A 10 week double blind study of 24 agoraphobics and 16 social phobics all on clomipramine compared the effect of adding tryptophan or placebo. Tryptophan did not potentiate the beneficial effect of clomipramine on phobic avoidance, phobic fears or the incidence of panic attacks. Neither was the presence of depression a factor of outcome.

摘要

一项针对24名广场恐惧症患者和16名社交恐惧症患者的为期10周的双盲研究，所有患者均服用氯米帕明，比较了添加色氨酸或安慰剂的效果。色氨酸并未增强氯米帕明对恐惧回避、恐惧情绪或惊恐发作发生率的有益作用。抑郁的存在也不是影响结果的因素。

相似文献

1
Does tryptophan potentiate clomipramine in the treatment of agoraphobic and social phobic patients?色氨酸在治疗广场恐怖症和社交恐惧症患者时会增强氯米帕明的疗效吗？
Br J Psychiatry. 1982 May;140:484-90. doi: 10.1192/bjp.140.5.484.
2
Clomipramine treatment of agoraphobic women. An eight-week controlled trial.氯米帕明治疗广场恐怖症女性：一项为期八周的对照试验。
Arch Gen Psychiatry. 1988 May;45(5):453-9. doi: 10.1001/archpsyc.1988.01800290073009.
3
Panic attacks and agoraphobia: low dose clomipramine treatment.惊恐发作与广场恐惧症：低剂量氯米帕明治疗
J Clin Psychopharmacol. 1989 Feb;9(1):28-32.
4
Clomipramine and diazepam in the treatment of agoraphobia and social phobia in general practice.氯米帕明与地西泮在全科医疗中治疗广场恐惧症和社交恐惧症的应用
Curr Med Res Opin. 1984;9(1):64-70. doi: 10.1185/03007998409109561.
5
Therapeutic response to phenelzine in patients with panic disorder and agoraphobia with panic attacks.对伴有惊恐发作的惊恐障碍和广场恐怖症患者使用苯乙肼的治疗反应。
J Clin Psychiatry. 1987 Feb;48(2):55-9.
6
Clomipramine in the treatment of agoraphobic inpatients resistant to behavioral therapy.氯米帕明治疗对行为疗法有抗药性的广场恐怖症住院患者。
J Clin Psychiatry. 1993 Dec;54(12):481-7.
7
The placebo effect in agoraphobia.
J Nerv Ment Dis. 1987 Feb;175(2):95-9. doi: 10.1097/00005053-198702000-00005.
8
An uncontrolled trial of clomipramine (Anafranil) in the treatment of phobic and obsessional states in general practice.氯米帕明（安拿芬尼）治疗全科医疗中恐惧症和强迫症的非对照试验。
J Int Med Res. 1977;5 Suppl 5:111-5.
9
Double-blind controlled study in phobias and obsessions.恐惧症和强迫症的双盲对照研究。
J Int Med Res. 1977;5 Suppl 5:42-8.
10
Lithium and tryptophan augmentation in clomipramine-resistant obsessive-compulsive disorder.锂盐和色氨酸增强氯米帕明对难治性强迫症的疗效
Am J Psychiatry. 1984 Oct;141(10):1283-5. doi: 10.1176/ajp.141.10.1283.

引用本文的文献

1
Pharmacotherapy for social anxiety disorder (SAnD).社交焦虑障碍的药物治疗
Cochrane Database Syst Rev. 2017 Oct 19;10(10):CD001206. doi: 10.1002/14651858.CD001206.pub3.
2
Tryptophan research in panic disorder.惊恐障碍中的色氨酸研究。
Int J Tryptophan Res. 2008;1:3-12. doi: 10.4137/ijtr.s929. Epub 2008 Aug 14.
3
A risk-benefit assessment of buspirone in the treatment of anxiety disorders.丁螺环酮治疗焦虑症的风险效益评估。
Drug Saf. 1997 Feb;16(2):118-32. doi: 10.2165/00002018-199716020-00004.
4
Psychopharmacological treatment of social phobia; a double blind placebo controlled study with fluvoxamine.社交恐惧症的精神药理学治疗；一项使用氟伏沙明的双盲安慰剂对照研究。
Psychopharmacology (Berl). 1994 Jun;115(1-2):128-34. doi: 10.1007/BF02244762.
5
Fluoxetine in panic disorder: pharmacologic and tritiated platelet imipramine and paroxetine binding study.氟西汀治疗惊恐障碍：药理学及血小板中氚标记的丙咪嗪和帕罗西汀结合研究
J Psychiatry Neurosci. 1995 May;20(3):193-8.
6
Recent developments in the psychopharmacology of social phobia.社交恐惧症心理药理学的最新进展。
Eur Arch Psychiatry Clin Neurosci. 1995;244(6):309-16. doi: 10.1007/BF02190409.
7
Behavioral, biochemical, and blood pressure responses to alprazolam in healthy subjects: interactions with yohimbine.健康受试者对阿普唑仑的行为、生化及血压反应：与育亨宾的相互作用。
Psychopharmacology (Berl). 1986;88(2):133-40. doi: 10.1007/BF00652229.
8
Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder.
Drugs. 1990 Jan;39(1):136-53. doi: 10.2165/00003495-199039010-00010.