色氨酸在治疗广场恐怖症和社交恐惧症患者时会增强氯米帕明的疗效吗？
Does tryptophan potentiate clomipramine in the treatment of agoraphobic and social phobic patients?
作者信息
Pecknold J C, McClure D J, Appeltauer L, Allan T, Wrzesinski L
出版信息
Br J Psychiatry. 1982 May;140:484-90. doi: 10.1192/bjp.140.5.484.
PMID:7049293
Abstract
A 10 week double blind study of 24 agoraphobics and 16 social phobics all on clomipramine compared the effect of adding tryptophan or placebo. Tryptophan did not potentiate the beneficial effect of clomipramine on phobic avoidance, phobic fears or the incidence of panic attacks. Neither was the presence of depression a factor of outcome.
摘要
一项针对24名广场恐惧症患者和16名社交恐惧症患者的为期10周的双盲研究，所有患者均服用氯米帕明，比较了添加色氨酸或安慰剂的效果。色氨酸并未增强氯米帕明对恐惧回避、恐惧情绪或惊恐发作发生率的有益作用。抑郁的存在也不是影响结果的因素。
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