环磷酰胺处理的棉鼠中的呼吸道合胞病毒感染
Respiratory syncytial virus infection in cyclophosphamide-treated cotton rats.
作者信息
Johnson R A, Prince G A, Suffin S C, Horswood R L, Chanock R M
出版信息
Infect Immun. 1982 Jul;37(1):369-73. doi: 10.1128/iai.37.1.369-373.1982.
Abstract
Cotton rats infected intranasally with respiratory syncytial virus and immunosuppressed with cyclophosphamide shed virus for at least 7 weeks. Dissemination of virus beyond the respiratory tract was observed. In contrast, virus was recovered from infected, non-immunosuppressed rats for only 1 week, and only from the respiratory tract.
摘要
经鼻腔感染呼吸道合胞病毒并用环磷酰胺进行免疫抑制的棉鼠排毒至少7周。观察到病毒传播至呼吸道以外的部位。相比之下，仅在感染的非免疫抑制大鼠的呼吸道中在1周内检测到病毒。
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