一项比较头孢克洛与复方新诺明治疗急性中耳炎疗效的试验。
A trial comparing cefaclor with co-trimoxazole in the treatment of acute otitis media.
作者信息
Feldman W, Richardson H, Rennie B, Dawson P
出版信息
Arch Dis Child. 1982 Aug;57(8):594-6. doi: 10.1136/adc.57.8.594.
Abstract
A prospective random double-blind controlled trial comparing the efficacy of cefaclor with that of co-trimoxazole in the treatment of otitis media was undertaken. Two hundred and twenty-three children aged 12 years or younger were studied. Both drugs were effective, with clinical cure or improvement in more than 90% of the children. The level of compliance was high and side effects few. Both co-trimoxazole and cefaclor can be considered safe and effective drugs for the treatment of acute otitis media.
摘要
进行了一项前瞻性随机双盲对照试验，比较头孢克洛与复方新诺明治疗中耳炎的疗效。研究了223名12岁及以下的儿童。两种药物均有效，超过90%的儿童实现了临床治愈或病情改善。依从性高，副作用少。复方新诺明和头孢克洛均可被视为治疗急性中耳炎的安全有效药物。
相似文献
1
A trial comparing cefaclor with co-trimoxazole in the treatment of acute otitis media.一项比较头孢克洛与复方新诺明治疗急性中耳炎疗效的试验。
Arch Dis Child. 1982 Aug;57(8):594-6. doi: 10.1136/adc.57.8.594.
2
A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media.头孢克洛与甲氧苄啶-磺胺甲恶唑治疗急性中耳炎的随机对照试验。
J Pediatr. 1984 Oct;105(4):633-8. doi: 10.1016/s0022-3476(84)80438-2.
3
Comparison of cefaclor and trimethoprim-sulfamethoxazole in the treatment of acute otitis media.头孢克洛与甲氧苄啶-磺胺甲恶唑治疗急性中耳炎的比较。
Pediatr Infect Dis. 1984 Jan-Feb;3(1):25-9. doi: 10.1097/00006454-198401000-00007.
4
[Cefaclor and trimethoprim-sulfamethoxazole for recurrent otitis media].[头孢克洛与甲氧苄啶-磺胺甲恶唑用于复发性中耳炎]
Harefuah. 1989 Dec 1;117(11):361-3.
5
Evaluation of cefaclor and amoxycillin in the treatment of acute otitis media.头孢克洛与阿莫西林治疗急性中耳炎的疗效评估。
Postgrad Med J. 1979;55 Suppl 4:39-41.
6
Comparison of cefaclor and amoxicillin for acute otitis media with effusion.头孢克洛与阿莫西林治疗分泌性中耳炎的比较。
Ann Otol Rhinol Laryngol Suppl. 1981 May-Jun;90(3 Pt 3):48-52. doi: 10.1177/00034894810903s212.
7
Amoxicillin-clavulanate potassium compared with cefaclor for acute otitis media in infants and children.阿莫西林克拉维酸钾与头孢克洛治疗婴幼儿急性中耳炎的比较。
Pediatr Infect Dis J. 1987 Mar;6(3):265-71. doi: 10.1097/00006454-198703000-00013.
8
Co-trimoxazole versus cefaclor in acute on chronic bronchitis.复方新诺明与头孢克洛治疗慢性支气管炎急性发作的对比
J Antimicrob Chemother. 1981 Dec;8(6):487-9. doi: 10.1093/jac/8.6.487.
9
Comparative efficacies of erythromycin-sulfisoxazole and cefaclor in acute otitis media: a double blind randomized trial.红霉素 - 磺胺异恶唑与头孢克洛治疗急性中耳炎的疗效比较：一项双盲随机试验。
Pediatr Infect Dis J. 1987 Jul;6(7):654-60. doi: 10.1097/00006454-198707000-00007.
10
Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media.甲氧苄啶-磺胺甲恶唑与阿莫西林治疗急性中耳炎的对比研究
CMAJ. 1988 Nov 15;139(10):961-4.
引用本文的文献
1
Application of Rank Annihilation Factor Analysis for Antibacterial Drugs Determination by Means of pH Gradual Change-UV Spectral Data.秩消因子分析在基于pH渐变-紫外光谱数据测定抗菌药物中的应用
Antibiotics (Basel). 2020 Jul 6;9(7):383. doi: 10.3390/antibiotics9070383.
2
Current antibiotic usage II: Aminoglycosides, tetracyclines, erythromycin, vancomycin and sulphonamides.当前抗生素的使用情况二：氨基糖苷类、四环素类、红霉素、万古霉素及磺胺类药物。
Indian J Pediatr. 1986 Mar-Apr;53(2):199-213. doi: 10.1007/BF02748508.
3
Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media.甲氧苄啶-磺胺甲恶唑与阿莫西林治疗急性中耳炎的对比研究
CMAJ. 1988 Nov 15;139(10):961-4.
本文引用的文献
1
Cefadroxil in the treatment of otitis media.
J Int Med Res. 1980;8(Suppl 1):103-5.
2
Acute otitis media: diagnosis and drug therapy.
Drugs. 1980 Feb;19(2):107-18. doi: 10.2165/00003495-198019020-00003.
3
Trimethoprim-sulfamethoxazole in the treatment of otitis media secondary to ampicillin-resistant strains of Haemophilus influenzae.甲氧苄啶-磺胺甲恶唑治疗由耐氨苄西林流感嗜血杆菌菌株引起的中耳炎
Ann Otol Rhinol Laryngol Suppl. 1980 May-Jun;89(3 Pt 2):281-4. doi: 10.1177/00034894800890s366.
4
Antibiotic-resistant bacteria in otitis media with effusion.分泌性中耳炎中的耐抗生素细菌。
Ann Otol Rhinol Laryngol Suppl. 1980 May-Jun;89(3 Pt 2):278-80. doi: 10.1177/00034894800890s365.
5
Cefaclor in treatment of otitis media and pharyngitis in children.头孢克洛治疗儿童中耳炎和咽炎。
Am J Dis Child. 1980 Jun;134(6):560-3. doi: 10.1001/archpedi.1980.02130180018006.
6
Management of acute otitis media.急性中耳炎的管理
Lancet. 1982 Jan 9;1(8263):111. doi: 10.1016/s0140-6736(82)90250-1.
7
Therapy of acute otitis media: myringotomy, antibiotics, or neither? A double-blind study in children.急性中耳炎的治疗：鼓膜切开术、抗生素，还是两者都不用？一项针对儿童的双盲研究。
Lancet. 1981 Oct 24;2(8252):883-7. doi: 10.1016/s0140-6736(81)91388-x.
8
Recurrence of otitis media after antibiotic therapy: comparison of cephradine and amoxycillin.抗生素治疗后中耳炎的复发：头孢拉定与阿莫西林的比较
J Int Med Res. 1979;7(6):546-50. doi: 10.1177/030006057900700613.
Zotero 插件