Kopp N, Claustrat B, Tappaz M
Neurosci Lett. 1980 Oct 2;19(3):237-42. doi: 10.1016/0304-3940(80)90267-0.
Melatonin was measured by radioimmunoassay in human brain and pineal gland. Levels were 50 times lower in brain than in pineal. The distribution appeared uneven between the various areas studied. No measurable hydroxyindol-O-methyltransferase activity could be shown. These findings suggest that what appears to be melatonin in the human brain is unlikely to be synthesized in situ.
通过放射免疫分析法对人脑中的褪黑素以及松果体进行了测定。脑内的褪黑素水平比松果体中的低50倍。在所研究的各个区域之间，其分布似乎并不均匀。未检测到可测量的羟基吲哚-O-甲基转移酶活性。这些发现表明，人脑中看似褪黑素的物质不太可能在原位合成。
