子宫内膜癌发病率的下降：对公共卫生的影响
The decreasing incidence of endometrial cancer: public health implications.
作者信息
Austin D F, Roe K M
出版信息
Am J Public Health. 1982 Jan;72(1):65-8. doi: 10.2105/ajph.72.1.65.
Abstract
The incidence of endometrial cancer in the San Francisco area between 1969 and 1979 is compared to trends in estrogen sales and prescriptions. Both estrogen use and endometrial cancer incidence increased steadily until 1975 and then decreased significantly. The data support the previously documented association between endometrial cancer and estrogen use, but suggest that short-term usage may carry only slightly increased risk which can be eliminating entirely upon termination of therapy.
摘要
将1969年至1979年旧金山地区子宫内膜癌的发病率与雌激素销售和处方趋势进行了比较。在1975年之前，雌激素的使用和子宫内膜癌的发病率均稳步上升，之后则显著下降。这些数据支持了先前记录的子宫内膜癌与雌激素使用之间的关联，但表明短期使用可能只会带来略微增加的风险，而这种风险在治疗终止后可完全消除。
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本文引用的文献
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Declining rates of endometrial cancer.子宫内膜癌发病率下降。
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Risk of exogenous estrogen therapy and endometrial cancer.外源性雌激素疗法与子宫内膜癌的风险。
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N Engl J Med. 1975 Dec 4;293(23):1164-7. doi: 10.1056/NEJM197512042932302.
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N Engl J Med. 1979 Feb 1;300(5):218-22. doi: 10.1056/NEJM197902013000502.
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Endometrial cancer in relation to patterns of menopausal estrogen use.子宫内膜癌与绝经后雌激素使用模式的关系
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