长期给予1,2 - 二甲基肼和二乙基亚硝胺对大鼠肝脏靶细胞群和非靶细胞群中细胞复制及DNA非预定合成的影响。 - Suppr

Suppr

超能文献

Effect of 1,2-dimethylhydrazine and diethylnitrosamine on cell replication and unscheduled DNA synthesis in target and nontarget cell populations in rat liver following chronic administration.

作者信息

Lewis J G, Swenberg J A

出版信息

Cancer Res. 1982 Jan;42(1):89-92.

PMID:7053871

Abstract

摘要

相似文献

Effect of 1,2-dimethylhydrazine and diethylnitrosamine on cell replication and unscheduled DNA synthesis in target and nontarget cell populations in rat liver following chronic administration.长期给予1,2 - 二甲基肼和二乙基亚硝胺对大鼠肝脏靶细胞群和非靶细胞群中细胞复制及DNA非预定合成的影响。

Cancer Res. 1982 Jan;42(1):89-92.

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Differential repair of O4-alkylthymidine following exposure to methylating and ethylating hepatocarcinogens.暴露于甲基化和乙基化肝癌致癌物后O4-烷基胸苷的差异修复

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[Accumulation of methylated purines in the liver and large intestine DNA of rats following repeated administrations of 1,2-dimethylhydrazine].[多次给予1,2-二甲基肼后大鼠肝脏和大肠DNA中甲基化嘌呤的积累]

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Selective inhibition of replicative and repair DNA synthesis in mouse colon following administration of 1,2-dimethylhydrazine.给予1,2-二甲基肼后对小鼠结肠中复制性和修复性DNA合成的选择性抑制。

J Toxicol Environ Health. 1984;13(1):117-24. doi: 10.1080/15287398409530485.

[Mechanism of methylation of DNA bases by symmetrical dimethylhydrazine].

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Formation of O6-methylguanine by alkylation of rat liver, colon, and kidney DNA following administration of 1,2-dimethylhydrazine.给予1,2-二甲基肼后大鼠肝脏、结肠和肾脏DNA烷基化形成O6-甲基鸟嘌呤。

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The kinetics of DNA alkylation, repair and replication in hepatocytes, Kupffer cells, and sinusoidal endothelial cells in rat liver during continuous exposure to 1,2-dimethylhydrazine.大鼠肝脏中肝细胞、库普弗细胞和窦状内皮细胞在持续暴露于1,2 - 二甲基肼期间DNA烷基化、修复和复制的动力学

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Formation and subsequent excision of O6-ethylguanine from DNA of rat liver following administration of diethylnitrosamine.给予二乙基亚硝胺后大鼠肝脏DNA中O6-乙基鸟嘌呤的形成及随后的切除

Cancer Res. 1979 Dec;39(12):5003-9.

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O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine.在持续接触二乙基亚硝胺的大鼠肝细胞DNA中，O4-乙基脱氧胸苷会累积，而O6-乙基脱氧鸟苷则不会。

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