给予1,2-二甲基肼后大鼠肝脏、结肠和肾脏DNA烷基化形成O6-甲基鸟嘌呤。 - Suppr

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Formation of O6-methylguanine by alkylation of rat liver, colon, and kidney DNA following administration of 1,2-dimethylhydrazine.

作者信息

Rogers K J, Pegg A E

出版信息

Cancer Res. 1977 Nov;37(11):4082-7.

PMID:908041

Abstract

摘要

相似文献

Formation of O6-methylguanine by alkylation of rat liver, colon, and kidney DNA following administration of 1,2-dimethylhydrazine.给予1,2-二甲基肼后大鼠肝脏、结肠和肾脏DNA烷基化形成O6-甲基鸟嘌呤。

Cancer Res. 1977 Nov;37(11):4082-7.

1,2-Dimethylhydrazine-induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram.1,2-二甲基肼诱导大鼠各器官DNA碱基甲基化及双硫仑预处理的影响

Cancer Res. 1979 Feb;39(2 Pt 1):465-7.

[Accumulation of methylated purines in the liver and large intestine DNA of rats following repeated administrations of 1,2-dimethylhydrazine].[多次给予1,2-二甲基肼后大鼠肝脏和大肠DNA中甲基化嘌呤的积累]

Biull Eksp Biol Med. 1980 Nov;90(11):626-8.

In vivo kinetics of O6-methylguanine and 7-methylguanine formation and persistence in DNA of rats treated with symmetrical dimethylhydrazine.

Cancer Res. 1981 Oct;41(10):3967-72.

Cell specificity in hepatocarcinogenesis: preferential accumulation of O6-methylguanine in target cell DNA during continuous exposure to rats to 1,2-dimethylhydrazine.肝癌发生中的细胞特异性：在持续给大鼠注射1,2 - 二甲基肼期间，靶细胞DNA中O6 - 甲基鸟嘌呤的优先积累。

Cancer Res. 1982 Aug;42(8):3079-83.

DNA alkylation in mice with genetically different susceptibility to 1,2-dimethylhydrazine-induced colon carcinogenesis.对1,2 - 二甲基肼诱导的结肠癌发生具有不同遗传易感性的小鼠中的DNA烷基化

Cancer Res. 1978 Sep;38(9):3063-5.

[Mechanism of methylation of DNA bases by symmetrical dimethylhydrazine].

Biull Eksp Biol Med. 1978 Dec;86(12):679-81.

Alkylated purines in the DNA of various rat tissues after administration of 1,2-dimethylhydrazine.给予1,2 - 二甲基肼后大鼠各种组织DNA中的烷基化嘌呤

Chem Biol Interact. 1977 Aug;18(2):235-40. doi: 10.1016/0009-2797(77)90009-6.

Effects of selenium on 1,2-dimethylhydrazine metabolism and DNA alkylation.硒对1,2 - 二甲基肼代谢及DNA烷基化的影响。

Carcinogenesis. 1981;2(7):575-80. doi: 10.1093/carcin/2.7.575.

[Action mechanism of the carcinogen 1,2-dimethylhydrazine].[致癌物质1,2 - 二甲基肼的作用机制]

Verh Dtsch Ges Pathol. 1978;62:494.

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Cancer Sci. 2004 Jun;95(6):475-80. doi: 10.1111/j.1349-7006.2004.tb03235.x.

Folate depletion impairs DNA excision repair in the colon of the rat.叶酸缺乏会损害大鼠结肠中的DNA切除修复。

Gut. 1998 Jul;43(1):93-9. doi: 10.1136/gut.43.1.93.

Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate.二甲基肼诱导大鼠结肠p53基因外显子特异性DNA低甲基化。膳食叶酸的调节作用。

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Early alterations of apoptosis and cell proliferation in azoxymethane-initiated rat colonic epithelium.偶氮甲烷引发的大鼠结肠上皮细胞凋亡和细胞增殖的早期变化

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