给予1,2-二甲基肼后大鼠肝脏、结肠和肾脏DNA烷基化形成O6-甲基鸟嘌呤。 - Suppr

Suppr

超能文献

Formation of O6-methylguanine by alkylation of rat liver, colon, and kidney DNA following administration of 1,2-dimethylhydrazine.

作者信息

Rogers K J, Pegg A E

出版信息

Cancer Res. 1977 Nov;37(11):4082-7.

PMID:908041

Abstract

摘要

相似文献

Formation of O6-methylguanine by alkylation of rat liver, colon, and kidney DNA following administration of 1,2-dimethylhydrazine.

Cancer Res. 1977 Nov;37(11):4082-7.

1,2-Dimethylhydrazine-induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram.

Cancer Res. 1979 Feb;39(2 Pt 1):465-7.

[Accumulation of methylated purines in the liver and large intestine DNA of rats following repeated administrations of 1,2-dimethylhydrazine].

Biull Eksp Biol Med. 1980 Nov;90(11):626-8.

In vivo kinetics of O6-methylguanine and 7-methylguanine formation and persistence in DNA of rats treated with symmetrical dimethylhydrazine.

Cancer Res. 1981 Oct;41(10):3967-72.

Cell specificity in hepatocarcinogenesis: preferential accumulation of O6-methylguanine in target cell DNA during continuous exposure to rats to 1,2-dimethylhydrazine.

Cancer Res. 1982 Aug;42(8):3079-83.

DNA alkylation in mice with genetically different susceptibility to 1,2-dimethylhydrazine-induced colon carcinogenesis.

Cancer Res. 1978 Sep;38(9):3063-5.

[Mechanism of methylation of DNA bases by symmetrical dimethylhydrazine].

Biull Eksp Biol Med. 1978 Dec;86(12):679-81.

Alkylated purines in the DNA of various rat tissues after administration of 1,2-dimethylhydrazine.

Chem Biol Interact. 1977 Aug;18(2):235-40. doi: 10.1016/0009-2797(77)90009-6.

Effects of selenium on 1,2-dimethylhydrazine metabolism and DNA alkylation.

Carcinogenesis. 1981;2(7):575-80. doi: 10.1093/carcin/2.7.575.

[Action mechanism of the carcinogen 1,2-dimethylhydrazine].

Verh Dtsch Ges Pathol. 1978;62:494.

引用本文的文献

Non-Canonical Helical Structure of Nucleic Acids Containing Base-Modified Nucleotides.

Int J Mol Sci. 2021 Sep 2;22(17):9552. doi: 10.3390/ijms22179552.

It takes a village: microbiota, parainflammation, paligenosis and bystander effects in colorectal cancer initiation.

Dis Model Mech. 2021 May 1;14(5). doi: 10.1242/dmm.048793. Epub 2021 May 10.

The role of one-electron reduction of lipid hydroperoxides in causing DNA damage.

Chemistry. 2009 Oct 12;15(40):10634-40. doi: 10.1002/chem.200900500.

Methylation of 2'-deoxyguanosine by a free radical mechanism.

J Phys Chem B. 2009 Sep 24;113(38):12773-81. doi: 10.1021/jp903554n.

Mouse models for the study of colon carcinogenesis.

Carcinogenesis. 2009 Feb;30(2):183-96. doi: 10.1093/carcin/bgn267. Epub 2008 Nov 26.

Eur J Nutr. 2008 Apr;47(3):161-70. doi: 10.1007/s00394-008-0711-1. Epub 2008 May 15.

Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents.

Cancer Sci. 2004 Jun;95(6):475-80. doi: 10.1111/j.1349-7006.2004.tb03235.x.

Folate depletion impairs DNA excision repair in the colon of the rat.

Gut. 1998 Jul;43(1):93-9. doi: 10.1136/gut.43.1.93.

Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate.

Am J Pathol. 1996 Oct;149(4):1129-37.

Early alterations of apoptosis and cell proliferation in azoxymethane-initiated rat colonic epithelium.

Jpn J Cancer Res. 1996 Jun;87(6):575-82. doi: 10.1111/j.1349-7006.1996.tb00262.x.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验