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良性食管狭窄保守治疗的结果:100例患者的随访研究

Results of conservative treatment of benign esophageal strictures: a follow-up study in 100 patients.

作者信息

Wesdorp I C, Bartelsman J F, den Hartog Jager F C, Huibregtse K, Tytgat G N

出版信息

Gastroenterology. 1982 Mar;82(3):487-93.

PMID:7054043
Abstract

The results of a conservative treatment of benign esophageal strictures (68 peptic, 21 postsurgical, 2 caustic stenoses, 8 Schatzki rings, 1 esophageal web) were evaluated in 100 patients. Treatment consisted of dilatation either with Eder-Puestove olives or with mercury bougies up to 18-20 mm, or with both. In addition, all patients received antireflux therapy when indicated. The follow-up study lasted from 1-6 yr. The results show that 88 patients became symptom-free. In 4 patients the results were moderate (intermittent dilatation necessary), while there were three failures: all in patients with a severe ulcerating peptic reflux esophagitis with stenosis. They were treated by antireflux surgery. There were eight perforations; all patients survived after surgical (4) and conservative (4) treatment; 3 patients received further dilatation. Conservative dilatory treatment (up to 18-20 mm), combined with antireflux therapy when indicated, offers in general an adequate result in patients with benign esophageal strictures.

摘要

对100例良性食管狭窄(68例消化性狭窄、21例术后狭窄、2例腐蚀性狭窄、8例沙茨基环、1例食管蹼)保守治疗的结果进行了评估。治疗方法包括使用埃德尔-普斯托夫橄榄形探子或直径达18 - 20毫米的水银探条进行扩张,或两种方法联合使用。此外,所有患者在有指征时均接受抗反流治疗。随访研究持续了1至6年。结果显示,88例患者症状消失。4例患者治疗效果中等(需要间歇性扩张),有3例治疗失败:均为患有严重溃疡性消化性反流食管炎并伴有狭窄的患者,这些患者接受了抗反流手术治疗。发生了8例穿孔;所有患者经手术治疗(4例)和保守治疗(4例)后均存活;3例患者接受了进一步扩张治疗。对于良性食管狭窄患者,保守性扩张治疗(直径达18 - 20毫米)并在有指征时联合抗反流治疗,总体上能取得较好的效果。

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