Martin J K, van Heerden J A, Gaffey T A
Surgery. 1982 Jan;91(1):12-6.
To determine the incidence of synchronous bilateral breast cancer, 100 women receiving their initial treatment for primary breast cancer prospectively underwent biopsy of the opposite breast. No patient had a clinically detectable abnormality in the contralateral breast, but 2% had unsuspected invasive ductal carcinomas. An additional 5% had premalignant lesions. To determine the incidence of the development of metachronous breast cancer, 153 women who underwent surgical treatment of primary breast cancer between 1955 and 1979 were followed from 2 months to 26 years, with an average of 3.6 years. During that time, 3.9% developed metachronous carcinomas of the contralateral breast.
为确定同步双侧乳腺癌的发病率，100名接受原发性乳腺癌初始治疗的女性前瞻性地接受了对侧乳房活检。对侧乳房在临床上均未发现异常，但有2%的患者存在未被怀疑的浸润性导管癌。另有5%的患者存在癌前病变。为确定异时性乳腺癌的发病率，对1955年至1979年间接受原发性乳腺癌手术治疗的153名女性进行了2个月至26年的随访，平均随访时间为3.6年。在此期间，3.9%的患者发生了对侧乳房异时性癌。
