Fulton D S, Marton L J, Lubich W P, Wilson C B
Arch Neurol. 1982 Jan;39(1):47-8. doi: 10.1001/archneur.1982.00510130049012.
Cerebrospinal fluid polyamine determinations were performed in 21 patients harboring pituitary tumors and six patients with nonneoplastic pituitary disease. Although CSF putrescine levels were significantly elevated in some patients harboring tumors, other patients showed no elevation. Polyamine levels did not correlate with tumor size, as assessed by the presence or absence of suprasellar extension. Data on patients harboring nonneoplastic pituitary disease were variable. Compared with other findings from this laboratory on the use of polyamine levels for the diagnosis and management of other brain tumors, these findings suggest that CSF polyamine levels will not have a significant diagnostic role in the treatment of patients suspected to have pituitary disease.
对21例患有垂体肿瘤的患者和6例患有非肿瘤性垂体疾病的患者进行了脑脊液多胺测定。虽然一些患有肿瘤的患者脑脊液腐胺水平显著升高，但其他患者并未升高。多胺水平与肿瘤大小无关，这是通过是否存在鞍上扩展来评估的。患有非肿瘤性垂体疾病患者的数据各不相同。与该实验室关于使用多胺水平诊断和管理其他脑肿瘤的其他研究结果相比，这些结果表明脑脊液多胺水平在疑似患有垂体疾病患者的治疗中不会发挥显著的诊断作用。
