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脑肿瘤患者脑脊液中多胺浓度升高。

Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors.

作者信息

Marton L J, Heby O, Wilson C B

出版信息

Int J Cancer. 1974 Dec 15;14(6):731-5. doi: 10.1002/ijc.2910140606.

DOI:10.1002/ijc.2910140606
PMID:4377003
Abstract

An automated method for the quantitative analysis of the polyamines putrescine, spermidine and spermine in cerebrospinal fluid (CSF) was used to analyze CSF samples from 37 patients with central nervous system (CNS) tumors and from 13 patients without tumors. The putrescine and spermidine concentrations in the CSF of most patients in tumors, particularly those with glioblastomas or medulloblastomas, were elevated when compared with those of non-tumor-bearing patients.

摘要

采用一种自动方法对脑脊液(CSF)中的多胺腐胺、亚精胺和精胺进行定量分析,以分析37例中枢神经系统(CNS)肿瘤患者和13例无肿瘤患者的脑脊液样本。与无肿瘤患者相比,大多数肿瘤患者,尤其是胶质母细胞瘤或髓母细胞瘤患者脑脊液中的腐胺和亚精胺浓度升高。

相似文献

1
Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors.脑肿瘤患者脑脊液中多胺浓度升高。
Int J Cancer. 1974 Dec 15;14(6):731-5. doi: 10.1002/ijc.2910140606.
2
The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors.脑脊液中多胺与中枢神经系统肿瘤存在的关系。
Cancer Res. 1976 Mar;36(3):973-7.
3
CSF polyamines. Potential as brain tumor markers.脑脊液多胺。作为脑肿瘤标志物的潜力。
Arch Neurol. 1981 Feb;38(2):73-4. doi: 10.1001/archneur.1981.00510020031002.
4
Evaluation of polyamine levels in cerebrospinal fluid of children with brain tumors.脑肿瘤患儿脑脊液中多胺水平的评估。
J Neurooncol. 1986;3(4):327-33. doi: 10.1007/BF00165581.
5
Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors.脑脊液多胺:儿童恶性脑肿瘤的生化标志物
Ann Neurol. 1986 Apr;19(4):360-4. doi: 10.1002/ana.410190409.
6
CSF polyamines in childhood.儿童脑脊液中的多胺
Arch Neurol. 1983 Apr;40(4):237-40. doi: 10.1001/archneur.1983.04050040067011.
7
Polyamine levels in CSF from patients with pituitary tumors or nonneoplastic pituitary disease.垂体肿瘤或非肿瘤性垂体疾病患者脑脊液中的多胺水平。
Arch Neurol. 1982 Jan;39(1):47-8. doi: 10.1001/archneur.1982.00510130049012.
8
Cytopathology of the cerebrospinal fluid examined with the sedimentation technique after Sayk.采用赛克(Sayk)沉淀技术检查脑脊液的细胞病理学。
J Neurol Sci. 1969 Jul-Aug;9(1):155-77. doi: 10.1016/0022-510x(69)90066-5.
9
Predictive value of cerebrospinal fluid polyamines in medulloblastoma.髓母细胞瘤中脑脊液多胺的预测价值
Cancer Res. 1979 Mar;39(3):993-7.
10
[Electrophoretic study of cerebrospinal fluid proteins in 104 cases of neuraxis tumors].[104例神经轴肿瘤患者脑脊液蛋白质的电泳研究]
Rev Neurol (Paris). 1972 Nov;127(5):505-15.

引用本文的文献

1
Insights into the glioblastoma tumor microenvironment: current and emerging therapeutic approaches.胶质母细胞瘤肿瘤微环境的见解:当前及新兴的治疗方法
Front Pharmacol. 2024 Mar 8;15:1355242. doi: 10.3389/fphar.2024.1355242. eCollection 2024.
2
Polyamines in human brain tumors. A correlative study between tumor, cerebrospinal fluid and red blood cell free polyamine levels.人脑肿瘤中的多胺。肿瘤、脑脊液和红细胞游离多胺水平之间的相关性研究。
J Neurooncol. 1984;2(2):153-8. doi: 10.1007/BF00177902.
3
Evaluation of polyamine levels in cerebrospinal fluid of children with brain tumors.
脑肿瘤患儿脑脊液中多胺水平的评估。
J Neurooncol. 1986;3(4):327-33. doi: 10.1007/BF00165581.
4
Serial lumbar and ventricle cerebrospinal fluid lactate dehydrogenase activities in patients with leptomeningeal metastases from solid and haematological tumours.实体瘤和血液系统肿瘤软脑膜转移患者的连续腰椎和脑室脑脊液乳酸脱氢酶活性
J Neurol Neurosurg Psychiatry. 1987 Mar;50(3):313-20. doi: 10.1136/jnnp.50.3.313.
5
Measurements of CSF biochemical tumor markers in patients with meningeal carcinomatosis and brain tumors.脑膜癌病和脑肿瘤患者脑脊液生化肿瘤标志物的检测
J Neurooncol. 1992 Feb;12(2):111-20. doi: 10.1007/BF00172659.
6
4-aminobutyrate in mammalian putrescine catabolism.哺乳动物腐胺分解代谢中的4-氨基丁酸
Biochem J. 1975 Nov;152(2):201-10. doi: 10.1042/bj1520201.
7
Effects of polyamines and methylglyoxal bis(guanylhydrazone) on hepatic nuclear structure and deoxyribonucleic acid template activity.多胺和双(胍基腙)甲基乙二醛对肝细胞核结构及脱氧核糖核酸模板活性的影响。
Biochem J. 1975 Dec;151(3):505-12. doi: 10.1042/bj1510505.