Rabin E Z, Tattrie B
Biochim Biophys Acta. 1982 Feb 4;701(1):132-7. doi: 10.1016/0167-4838(82)90321-1.
A low molecular weight ribonuclease (Mr 18 000) isolated and purified from human uremic serum was found to have similar properties to the high molecular weight ribonuclease (Mr 33 000) isolated from human urine. A detailed comparative study of both enzymes was undertaken to investigate the relationship between them. It is suggested that poly(C)-avid human ribonucleases have similar amino acid compositions but variable carbohydrate contents and that variations in the sugar content are responsible for variations in the molecular weight.
从人尿毒症血清中分离纯化得到的一种低分子量核糖核酸酶（分子量18000），被发现与从人尿液中分离得到的高分子量核糖核酸酶（分子量33000）具有相似的性质。对这两种酶进行了详细的比较研究，以探讨它们之间的关系。结果表明，与聚（C）有亲和力的人核糖核酸酶具有相似的氨基酸组成，但碳水化合物含量不同，且糖含量的差异导致了分子量的差异。
