Duncan P, Gochman N, Bayse D, Burnett R, Carey N, Carter R, Fellows W D, Garber C, Kessler G, McComb R, Miller W, Nast P, Ryan W, Schaffer R, Tejeda B, Vanderlinde R, Widdowson G
Clin Chem. 1982 Feb;28(2):291-3.
We describe the interlaboratory testing of a candidate Reference Method (Part I) for uric acid in serum. The method is based on the ultrasound spectrophotometric quantitation of uric acid before and after incubation with uricase. A comprehensive investigation involving 12 laboratories was organized to document the transferability, intra- and interlaboratory precision, and general reliability of the candidate Reference Method. The interlaboratory CV with this method was about 2 to 6% for uric acid concentrations ranging from 0.12 to 0.60 mmol/L. The results detailed here demonstrate that the method can be successfully duplicated among different laboratories.
我们描述了血清中尿酸候选参考方法（第一部分）的实验室间测试。该方法基于尿酸酶孵育前后尿酸的超声分光光度法定量。组织了一项涉及12个实验室的全面调查，以记录候选参考方法的可转移性、批内和批间精密度以及总体可靠性。对于尿酸浓度范围为0.12至0.60 mmol/L的情况，该方法的实验室间变异系数约为2%至6%。此处详述的结果表明，该方法可在不同实验室之间成功复制。
