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Cytochrome P-450scc-substrate interactions. Studies of binding and catalytic activity using hydroxycholesterols.

作者信息

Lambeth J D, Kitchen S E, Farooqui A A, Tuckey R, Kamin H

出版信息

J Biol Chem. 1982 Feb 25;257(4):1876-84.

PMID:7056749
Abstract
摘要

相似文献

1
Cytochrome P-450scc-substrate interactions. Studies of binding and catalytic activity using hydroxycholesterols.细胞色素P-450侧链裂解酶-底物相互作用。使用羟基胆固醇进行的结合和催化活性研究。
J Biol Chem. 1982 Feb 25;257(4):1876-84.
2
Effects of phospholipid and detergent on the substrate specificity of adrenal cytochrome P-450scc. Substrate binding and kinetics of cholesterol side chain oxidation.磷脂和去污剂对肾上腺细胞色素P-450scc底物特异性的影响。底物结合及胆固醇侧链氧化动力学。
J Biol Chem. 1981 May 10;256(9):4407-17.
3
22-Ketocholesterol. A potent competitive inhibitor of cytochrome P-450scc-dependent side-chain cleavage of cholesterol.22-酮胆固醇。一种对细胞色素P-450scc依赖性胆固醇侧链裂解具有强效竞争性抑制作用的物质。
Mol Pharmacol. 1983 May;23(3):743-7.
4
Adrenal mitochondrial cytochrome P-450scc. Cholesterol and adrenodoxin interactions at equilibrium and during turnover.肾上腺线粒体细胞色素P - 450scc。胆固醇与肾上腺铁氧化还原蛋白在平衡状态及周转过程中的相互作用。
J Biol Chem. 1981 May 10;256(9):4321-8. doi: 10.1016/S0021-9258(19)69436-6.
5
[Immunochemical characteristics of cholesterol-hydroxylating cytochrome P-450 from adrenal cortex mitochondria].[肾上腺皮质线粒体胆固醇羟化细胞色素P-450的免疫化学特性]
Biokhimiia. 1984 Nov;49(11):1810-8.
6
Phospholipid vesicle-reconstituted cytochrome P-450SCC. Mutually facilitated binding of cholesterol and adrenodoxin.
J Biol Chem. 1980 Jan 10;255(1):138-43.
7
Protein rotation study of cytochrome P-450 in submitochondrial particles: effect of KCl and intermolecular interactions with redox partners.
J Biochem. 1991 Apr;109(4):594-9. doi: 10.1093/oxfordjournals.jbchem.a123425.
8
The transfer of cholesterol and hydroxycholesterol derivatives from liposome to soluble cytochrome P-450 scc.胆固醇和羟基胆固醇衍生物从脂质体到可溶性细胞色素P-450 scc的转移。
Biochim Biophys Acta. 1981 Dec 23;666(3):370-81. doi: 10.1016/0005-2760(81)90296-4.
9
The role of the sugar regions of components of the cytochrome P-450-linked mixed-function oxidase (monooxygenase) system of bovine adrenocortical mitochondria.牛肾上腺皮质线粒体中细胞色素P - 450相关混合功能氧化酶（单加氧酶）系统各组分糖区域的作用。
Biochim Biophys Acta. 1982 Jul 12;705(1):82-91. doi: 10.1016/0167-4838(82)90339-9.
10
The relationship between NADPH-dependent lipid peroxidation and degradation of cytochrome P-450 in adrenal cortex mitochondria.肾上腺皮质线粒体中烟酰胺腺嘌呤二核苷酸磷酸（NADPH）依赖性脂质过氧化与细胞色素P - 450降解之间的关系。
Biochem Biophys Res Commun. 1983 Jan 27;110(2):559-66. doi: 10.1016/0006-291x(83)91186-5.

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细胞色素 P450 研究与 。
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J Steroid Biochem Mol Biol. 2018 Mar;177:59-69. doi: 10.1016/j.jsbmb.2017.07.011. Epub 2017 Jul 14.
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Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.人源和鼠源 CYP27B1 对 CYP11A1 来源的维生素 D3 代谢产物的羟化作用。
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Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity.大鼠 CYP24A1 作用于 20-羟基维生素 D(3)，生成具有增强生物学活性的羟化产物。
Biochem Pharmacol. 2012 Dec 15;84(12):1696-704. doi: 10.1016/j.bcp.2012.09.032. Epub 2012 Oct 5.
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Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones.鉴定一种驱动胆固醇导入、运输并代谢为类固醇激素的动态线粒体蛋白复合物。
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