Fischer E G, Sotrel A, Welch K
J Neurosurg. 1982 Mar;56(3):430-4. doi: 10.3171/jns.1982.56.3.0430.
Two patients are reported who had intracerebral mass lesions composed of hemangioma and glial neoplasm. After excision, one recurred as an oligodendroglioma, and the remnant of the other remained static over a 5-year period. These lesions may represent a subgroup of cerebral hemangiomas that have the biological potential for future glial neoplastic growth. Reference is made to experimental work with polyoma virus which can induce cavernous hemangiomas in the central nervous system in mice, and which is a papovavirus. Other papovaviruses can induce ependymomas in hamsters.
报告了两名患有由血管瘤和神经胶质瘤组成的脑内肿块病变的患者。切除后,一名患者复发为少突胶质细胞瘤,另一名患者的残余病变在5年期间保持稳定。这些病变可能代表了具有未来神经胶质肿瘤生长生物学潜能的脑血管瘤亚组。文中提到了用多瘤病毒进行的实验工作,该病毒可在小鼠中枢神经系统中诱导海绵状血管瘤,且它是一种乳头多瘤空泡病毒。其他乳头多瘤空泡病毒可在仓鼠中诱导室管膜瘤。