Khan O, Williams G, Chisholm G D, Welbourn R B
J R Soc Med. 1982 Jan;75(1):17-20. doi: 10.1177/014107688207500105.
Phaeochromocytomas of the bladder are rare, only about 100 cases having been reported previously. Four adults with these lesions have been managed at Hammersmith Hospital in the past 10 years. Three patients had hypertension, together with syncopal attacks and/or headaches, induced by micturition. The fourth patient presented with haematuria. After control of blood pressure and localization of the tumours by various combinations of cystoscopy, intravenous urography, venous sampling, ultrasound, angiography and computerized coaxial tomography (CT scanning), 3 patients underwent partial cystectomy, and the fourth pelvic exenteration. Two patients were apparently cured of the disease, but 2 were not. One developed modal metastases and recurrence of hypertension after 18 months and one rapidly developed metastases in the lungs and elsewhere. Effective therapy probably requires a high index of suspicion in diagnosing the condition and possibly an aggressive surgical and radiotherapeutic policy.
膀胱嗜铬细胞瘤很罕见，此前仅有约100例相关病例报道。在过去10年里，伦敦哈默史密斯医院收治了4例患有此类病变的成人患者。3例患者有高血压，伴有排尿诱发的晕厥发作和/或头痛。第4例患者表现为血尿。通过膀胱镜检查、静脉肾盂造影、静脉采血、超声、血管造影和计算机断层扫描（CT扫描）等多种方法控制血压并对肿瘤进行定位后，3例患者接受了膀胱部分切除术，第4例患者接受了盆腔脏器清除术。2例患者病情明显治愈，但另外2例未治愈。1例患者在18个月后出现远处转移和高血压复发，另1例患者肺部及其他部位迅速出现转移。有效的治疗可能需要在诊断该病时保持高度警惕，或许还需要采取积极的手术和放射治疗策略。
