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左旋咪唑治疗克罗恩病

Levamisole in the treatment of Crohn's disease.

作者信息

Segal A W, Levi A J, Loewi G

出版信息

Lancet. 1977 Aug 20;2(8034):382-5. doi: 10.1016/s0140-6736(77)90307-5.

Abstract

In 8 patients with active uncomplicated Crohn's disease who were not receiving any specific therapy, a clinical remission was induced with an elemental diet, and then an attempt was made to maintain this remission with levamisole. This regimen resulted in excellent control of the disease. A drug-induced arthritis developed in two patients and resolved spontaneously. There were no other significant side-effects.

摘要

在8例未接受任何特异性治疗的活动性非复杂性克罗恩病患者中,采用要素饮食诱导临床缓解,然后尝试用左旋咪唑维持这种缓解状态。该治疗方案使疾病得到了很好的控制。两名患者出现了药物性关节炎,但均自行缓解。未出现其他明显的副作用。

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