O'Morain C, Segal A W, Levi A J
Br Med J. 1980 Nov 1;281(6249):1173-5. doi: 10.1136/bmj.281.6249.1173.
Twenty-seven patients with 32 acute exacerbations of Crohn's disease were treated for four weeks with an elemental diet. At the end of treatment 29 of the exacerbations had remitted both clinically and biochemically. After six months six patients had relapsed. These findings suggest that the elemental diet is effective in treating acute Crohn's disease, but the reasons are not clear. The diet may be effective because it provides nutritional support, is hypoallergenic, acts as a medical bypass from the affected area, or alters bowel flora. The patient's general wellbeing is improved by the supply of adequate energy and essential foodstuffs in a form easily available without further digestion and given in a safe, simple, non-toxic way.
27例患有32次克罗恩病急性加重期的患者接受了四周的要素饮食治疗。治疗结束时，29次加重期在临床和生化方面均已缓解。六个月后，有6名患者复发。这些发现表明要素饮食对治疗急性克罗恩病有效，但原因尚不清楚。这种饮食可能有效，因为它提供营养支持、低过敏性、起到绕过患病区域的医学作用，或改变肠道菌群。通过以无需进一步消化即可轻易获取的形式提供充足的能量和必需食物，并以安全、简单、无毒的方式给予，患者的总体健康状况得到改善。
