Meckes M C
Appl Environ Microbiol. 1982 Feb;43(2):371-7. doi: 10.1128/aem.43.2.371-377.1982.
Total coliforms and total coliforms resistant to streptomycin, tetracycline, or chloramphenicol were isolated from filtered activated sludge effluents before and after UV light irradiation. Although the UV irradiation effectively disinfected the wastewater effluent, the percentage of the total surviving coliform population resistant to tetracycline or chloramphenicol was significantly higher than the percentage of the total coliform population resistant to those antibiotics before UV irradiation. This finding was attributed to the mechanism of R-factor-mediated resistance to tetracycline. No significant difference was noted for the percentage of the surviving total coliform population resistant to streptomycin before or after UV irradiation. Multiple drug resistance patterns of 300 total coliform isolates revealed that 82% were resistant to two or more antibiotics. Furthermore, 46% of these isolates were capable of transferring antibiotic resistance to a sensitive strain of Escherichia coli.
从紫外线照射前后的过滤活性污泥流出物中分离出总大肠菌群以及对链霉素、四环素或氯霉素具有抗性的总大肠菌群。尽管紫外线照射有效地对废水流出物进行了消毒，但存活的总大肠菌群中对四环素或氯霉素具有抗性的百分比显著高于紫外线照射前总大肠菌群中对这些抗生素具有抗性的百分比。这一发现归因于R因子介导的对四环素的抗性机制。紫外线照射前后，存活的总大肠菌群中对链霉素具有抗性的百分比没有显著差异。对300株总大肠菌群分离株的多重耐药模式分析表明，82%的分离株对两种或更多种抗生素具有抗性。此外，这些分离株中有46%能够将抗生素抗性转移至敏感的大肠杆菌菌株。
