Marsh E B, Smith D H
J Bacteriol. 1969 Oct;100(1):128-39. doi: 10.1128/jb.100.1.128-139.1969.
Two R factors which have the capacity to improve survival of some strains of Escherichia coli K-12 by approximately 60% after ultraviolet light have been identified and characterized. Both are fi(-), but neither produce colicins. The ability to enhance survival can be separated from all other identified R-factor functions. Improved survival does not result from improved excisional capacity, but does require an intact host capacity for genetic recombination. No effects on host cell growth or postirradiation lag were observed. A proposed mechanism of action is described.
已鉴定并表征了两种R因子，它们能够在紫外线照射后将某些大肠杆菌K-12菌株的存活率提高约60%。这两种R因子均为fi(-)，但均不产生大肠杆菌素。提高存活率的能力可以与所有其他已鉴定的R因子功能分离。存活率的提高并非源于切除能力的改善，但确实需要宿主具备完整的基因重组能力。未观察到对宿主细胞生长或照射后延迟的影响。本文描述了一种推测的作用机制。
