Ebright J R, Soin J S, Manoli R S
Arch Intern Med. 1982 Feb;142(2):246-54.
Gallium citrate Ga 67 (67Ga) has been used for almost ten years as a means of detecting inflammatory lesions in febrile patients. We have reviewed 80 cases from Milwaukee County General Hospital (1977 through 1979) in which 67Ga scanning was performed to detect inflammatory lesions in patients by suspected infection. Fifty scans also were available for review by the nuclear medicine staff. We found the sensitivity of 67Ga scans at our institution to be 90%, but specificity to be only 64%. In five (6%) of the cases, 67Ga scanning was the most important means of establishing a diagnosis. Of the 50 scans available for review, only 26 scans (52%) were interpreted in the same way as the original reading. Twenty-two (27%) of all scans in retrospect should not have been ordered, either because of the fever was gone and the patient's condition was improving or the diagnosis was already made. We conclude that 67Ga scans can be useful to detect inflammatory lesions but that they are frequently used inappropriately by physicians at our hospital, they are difficult to interpret, and the specificity is lower than the sensitivity.
枸橼酸镓Ga 67（67Ga）作为检测发热患者炎症性病变的一种手段已使用了近十年。我们回顾了密尔沃基县综合医院1977年至1979年期间的80例病例，这些病例均进行了67Ga扫描，以检测疑似感染患者的炎症性病变。核医学工作人员也可查看50份扫描结果。我们发现本院67Ga扫描的敏感性为90%，但特异性仅为64%。在5例（6%）病例中，67Ga扫描是确诊的最重要手段。在可供查看的50份扫描结果中，只有26份（52%）的解读与原始读数一致。回顾所有扫描结果，22份（27%）本不应进行检查，要么是因为发热已消退且患者病情正在好转，要么是因为诊断已经明确。我们得出结论，67Ga扫描有助于检测炎症性病变，但本院医生经常不恰当地使用它们，它们难以解读，且特异性低于敏感性。
