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系统性硬化症患者的心肌枸橼酸镓-67闪烁扫描术

Myocardial gallium-67 citrate scintigraphy in patients with systemic sclerosis.

作者信息

Gaál J, Hegedüs I, Dévényi K, Czirják L

机构信息

1st Department of Internal Medicine, University Medical School of Debrecen, Hungary.

出版信息

Ann Rheum Dis. 1995 Oct;54(10):856-8. doi: 10.1136/ard.54.10.856.

DOI:10.1136/ard.54.10.856
PMID:7492229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1010025/
Abstract

OBJECTIVE

To detect myocardial involvement in 16 patients with systemic sclerosis using radiogallium scintigraphy

METHODS

Sixteen patients with systemic sclerosis were investigated by myocardial gallium-67 citrate scintigraphy. Echocardiographic studies and (in the positive cases) magnetic resonance imaging were also performed.

RESULTS

Increased myocardial gallium uptake was found in five of the 16 patients. None of these positive cases exhibited any 'classical' clinical, electrocardiographic or laboratory signs characteristic of myocarditis. The mean age of the positive cases was 60.8 (SD 5.0) years compared with 44.6 (10.7) years for the negative cases; no difference was detected in the mean disease duration between these two groups. Two of the affected cases belonged to the limited scleroderma subgroup.

CONCLUSIONS

In spite of the low number of patients investigated, it is tempting to speculate that elderly patients with a disease onset around 60 years tend to be the candidates in whom a positive gallium-67 scintigraphy test may best indicate a silent myocardial interstitial inflammation.

摘要

目的

使用放射性镓闪烁扫描术检测16例系统性硬化症患者的心肌受累情况

方法

对16例系统性硬化症患者进行心肌枸橼酸镓-67闪烁扫描术检查。还进行了超声心动图研究以及(阳性病例)磁共振成像检查。

结果

16例患者中有5例心肌镓摄取增加。这些阳性病例均未表现出任何心肌炎典型的临床、心电图或实验室特征性表现。阳性病例的平均年龄为60.8(标准差5.0)岁,阴性病例为44.6(10.7)岁;两组间平均病程无差异。2例受累病例属于局限性硬皮病亚组。

结论

尽管研究的患者数量较少,但仍可推测,发病年龄在60岁左右的老年患者可能是镓-67闪烁扫描术检查结果呈阳性最能提示存在无症状心肌间质炎症的人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c9/1010025/2eb08de80bae/annrheumd00343-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c9/1010025/2eb08de80bae/annrheumd00343-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c9/1010025/2eb08de80bae/annrheumd00343-0077-a.jpg

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Cardiac and skeletal muscle disease in systemic sclerosis (scleroderma): a high risk association.系统性硬化症(硬皮病)中的心脏和骨骼肌疾病:一种高风险关联。
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