Shaxted E J, Heyes V M, Walker M P, Maynard P V
Br J Obstet Gynaecol. 1982 Jan;89(1):73-6. doi: 10.1111/j.1471-0528.1982.tb04640.x.
Plasma progesterone concentration was measured by radioimmunoassay in blood samples taken from 67 patients delivered by lower-segment caesarean section (LSCS). Blood samples were taken from umbilical-cord artery and vein and from a peripheral maternal vein. Cord venous progesterone levels were higher (c400 ng/ml) in those patients where the fetus was clinically in jeopardy and this was the principal indication for section. Patients in whom the fetus was not in jeopardy had lower cord venous progesterone concentrations (c300 ng/ml) regardless of whether or not they were in labour. Maternal levels of progesterone were similar in all patients. The advantage to the fetus of these varying progesterone concentrations is not clear, but the evidence lends support to the hypothesis that the fetus exercises control over placental progesterone production during parturition.
采用放射免疫分析法测定了67例经下段剖宫产（LSCS）分娩患者血样中的血浆孕酮浓度。血样取自脐动脉和脐静脉以及产妇外周静脉。在临床上胎儿处于危险状态的患者中，脐静脉孕酮水平较高（≥400 ng/ml），这是剖宫产的主要指征。无论是否处于分娩期，胎儿未处于危险状态的患者脐静脉孕酮浓度较低（<300 ng/ml）。所有患者的母体孕酮水平相似。这些不同孕酮浓度对胎儿的益处尚不清楚，但证据支持了胎儿在分娩过程中对胎盘孕酮产生进行控制的假说。
