Aisien A O, Towobola O A, Otubu J A, Imade G E
Department of Obstetrics and Gynaecology, Faculty of Medical Sciences, University of Jos, Plateau State, Nigeria.
Int J Gynaecol Obstet. 1994 Oct;47(1):27-31. doi: 10.1016/0020-7292(94)90457-x.
To determine whether the umbilical cord venous progesterone at term delivery is related to the mode of delivery.
Thirty-nine pregnant patients at term were divided into three groups: elective cesarean section (control), spontaneous vaginal delivery, and emergency cesarean section. Umbilical cord venous and maternal serum progesterone were measured by radioimmunoassay. Statistical analysis was carried out using Student's t-test, with the level of significance set at P < 0.05.
Umbilical cord venous progesterone was significantly higher in babies delivered by emergency cesarean section (P < 0.001) and in those who had spontaneous vaginal delivery (P < 0.02), compared with the control group. Maternal serum progesterone concentrations showed no significant differences between the three groups. The Apgar scores of the stressed group of babies were significantly lower (P < 0.001).
The findings demonstrate that the fetuses exposed to stress during labor produce higher progesterone secretion. This could be one possible way the fetus protects itself against the sequelae of hypoxia.
确定足月分娩时脐带静脉孕酮水平是否与分娩方式有关。
将39名足月孕妇分为三组：择期剖宫产（对照组）、自然阴道分娩和急诊剖宫产。采用放射免疫分析法测定脐带静脉和母体血清孕酮水平。使用学生t检验进行统计分析，显著性水平设定为P < 0.05。
与对照组相比，急诊剖宫产分娩的婴儿（P < 0.001）和自然阴道分娩的婴儿（P < 0.02）脐带静脉孕酮水平显著更高。三组母体血清孕酮浓度无显著差异。应激组婴儿的阿氏评分显著更低（P < 0.001）。
研究结果表明，分娩时受到应激的胎儿会产生更高的孕酮分泌。这可能是胎儿保护自身免受缺氧后遗症影响的一种可能方式。
