Jacobsen H, Busse H G, Havsteen B H
J Biol Chem. 1982 Apr 10;257(7):4001-6.
Stirred cytoplasmic extracts of the yeast Saccharomyces uvarum can, on addition of trehalose, display oscillations in the metabolite concentrations. Unstirred extracts may also develop spatiotemporal structures expressed in the metabolite concentrations. In this paper we present evidence of the existence of such patterns. The latter were recorded using the optical absorption of NADH in an annular cuvette, which was rotated in a photometer. Regularly spaced wavelike spatiotemporal standing waves were observed. At certain fixed points the NADH concentration appeared to remain constant. Such phenomena may improve our understanding of biochemical morphogenesis.
在添加海藻糖后，葡萄汁酵母的搅拌细胞质提取物中代谢物浓度会出现振荡。未搅拌的提取物也可能形成代谢物浓度所表现出的时空结构。在本文中，我们提供了此类模式存在的证据。后者是利用环形比色皿中烟酰胺腺嘌呤二核苷酸（NADH）的光吸收进行记录的，该比色皿在光度计中旋转。观察到了规则间隔的波状时空驻波。在某些固定点，NADH浓度似乎保持恒定。此类现象可能会增进我们对生化形态发生的理解。
