Proshliakova E V
Ontogenez. 1982;13(1):87-9.
The concentration of corticosterone in the suprarenals after the stress effect (injection of formol) was studied in 20.5 days old foetuses of the adrenalectomized rats, using the method of competitive binding. The concentration of corticosterone in the suprarenals of normal foetuses increased reliably within 30 min after the injection of formol; this reaction was absent in the encephalectomized foetuses. The results obtained suggest the participation of embryonic hypothalamus in the organization of stress response during prenatal development of rats.
采用竞争结合法，对肾上腺切除大鼠20.5日龄胎儿在应激作用（注射甲醛）后肾上腺中皮质酮的浓度进行了研究。正常胎儿注射甲醛后30分钟内，肾上腺中皮质酮的浓度可靠地升高；而脑切除胎儿则无此反应。所得结果表明，胚胎下丘脑参与了大鼠产前发育过程中应激反应的组织。
