Mishell D R
Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles 90033.
J Reprod Med. 1993 Dec;38(12 Suppl):1021-9.
The noncontraceptive health benefits of oral contraceptives were initially summarized a decade ago. Studies conducted in the last decade confirmed the findings of earlier studies with high-dose oral contraceptives and extended them to low-dose formulations. Among the noncontraceptive health benefits first cited were reductions in menorrhagia, irregular menses, endometrial cancer, ovarian cancer, functional ovarian cysts, benign breast disease, dysmenorrhea, premenstrual tension and iron-deficiency anemia. In addition, women who used oral contraceptives were less likely to develop rheumatoid arthritis or acute salpingitis, particularly moderate or severe forms, than were women using no method of contraception. Despite the fact that such benefits were identified more than 10 years ago and despite their inclusion in oral contraceptive labeling, women today are largely unaware of the noncontraceptive health benefits associated with oral contraceptive use.
口服避孕药的非避孕健康益处最初是在十年前进行总结的。过去十年开展的研究证实了早期关于高剂量口服避孕药研究的结果,并将其扩展至低剂量配方。最初列举的非避孕健康益处包括月经过多、月经不规律、子宫内膜癌、卵巢癌、功能性卵巢囊肿、良性乳腺疾病、痛经、经前紧张和缺铁性贫血的减少。此外,与未采用任何避孕方法的女性相比,使用口服避孕药的女性患类风湿性关节炎或急性输卵管炎(尤其是中度或重度形式)的可能性更低。尽管这些益处早在十多年前就已被发现,并且已列入口服避孕药的标签说明,但如今的女性大多并不了解与使用口服避孕药相关的非避孕健康益处。