Roberts S A, Soothill J F
Arch Dis Child. 1982 Feb;57(2):127-30. doi: 10.1136/adc.57.2.127.
The postweaning IgE and IgG antiovalbumin antibody responses were greater in rat pups which had received a cows' milk-based supplementary feed than in litter mates which had not. This effect was antigen non-specific and might be similar to that of supplementary feeds in the development of atopy in human infants. The total IgE concentration was similar in the two groups. Supplementary feeds did not increase the low values of IgE antiovalbumin in rats suckled by mothers immunised to ovalbumin.
断奶后,食用以牛奶为基础的补充饲料的大鼠幼崽,其抗卵清蛋白IgE和IgG抗体反应比未食用补充饲料的同窝幼崽更强。这种效应是非抗原特异性的,可能类似于补充饲料对人类婴儿特应性疾病发展的影响。两组的总IgE浓度相似。补充饲料并没有提高由对卵清蛋白免疫的母亲哺乳的大鼠中抗卵清蛋白IgE的低值。