系统性红斑狼疮患者的结核病
Tuberculosis in patients with systemic lupus erythematosus.
作者信息
Feng P H, Tan T H
出版信息
Ann Rheum Dis. 1982 Feb;41(1):11-4. doi: 10.1136/ard.41.1.11.
Abstract
Tuberculosis associated with systemic lupus erythematosus (SLE) was studied in a cohort of 311 patients seen between 1963 to 1979. There were 16 such patients, giving rise to a prevalence rate of 5%. The characteristics of SLE-associated tuberculosis include a high incidence of miliary and far-advanced pulmonary disease, delay in establishing diagnosis, especially the extrapulmonary form, and tendency to attribute symptoms like fever, malaise, and weight loss to the lupus process. Treatment was successful in 9 patients. Of the 7 death 5 were attributed directly to the mycobacterial infection and 2 to complications of SLE.
摘要
对1963年至1979年间就诊的311例系统性红斑狼疮（SLE）患者队列进行了与结核病相关的研究。其中有16例此类患者，患病率为5%。SLE相关结核病的特征包括粟粒性和晚期肺部疾病的高发病率、诊断延迟，尤其是肺外形式，以及倾向于将发热、不适和体重减轻等症状归因于狼疮病程。9例患者治疗成功。在7例死亡病例中，5例直接归因于分枝杆菌感染，2例归因于SLE并发症。
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