Hanel K C, McCabe C, Abbott W M, Fallon J, Megerman J
Ann Surg. 1982 Apr;195(4):456-63. doi: 10.1097/00000658-198204000-00012.
Two currently available brands of PTFE grafts (Goretex and Impra) were studied in a canine femoral artery model to determine whether changes in the manufacturing processes of the two grafts, which increased their strength, had altered the biophysical properties and the histological reactivity of either graft. Both grafts were found to be similar except for differences in their suturability. Their in vivo dynamic compliances were almost identical (1.2 +/- 0.35 vs. 1.2 +/- 0.45). (Scanning electron microscopy showed endothelialization of the grafts only adjacent to the anastomoses, and light microscopy demonstrated similar degrees of histologic incorporation by the host tissues, though of slower tempo than that previously described. These results are examined and discussed with regard to the suitability of this model for characterizing new arterial prostheses of small to medium diameter.
在犬股动脉模型中研究了两种市售的聚四氟乙烯移植物（戈尔特斯和英普拉），以确定两种移植物制造工艺的改变（这种改变增强了它们的强度）是否改变了任一移植物的生物物理特性和组织学反应性。结果发现，除了缝合性存在差异外，两种移植物相似。它们的体内动态顺应性几乎相同（1.2±0.35对1.2±0.45）。（扫描电子显微镜显示仅在吻合口附近的移植物有内皮化，光学显微镜显示宿主组织的组织学整合程度相似，尽管速度比先前描述的要慢。针对该模型用于表征中小直径新型动脉假体的适用性对这些结果进行了检验和讨论。
