Dougherty S H, Foster C A, Eisenberg M M
Arch Surg. 1982 Mar;117(3):294-7. doi: 10.1001/archsurg.1982.01380270022005.
The records of 1,079 patients with gastric carcinoma were reviewed. Of these, only 21 (about 2%) had had previous gastric surgery for benign disease, usually peptic ulcer. The average interval between the original gastric surgery and the discovery of stomach cancer was 26.9 years. The symptoms of cancer presentation were not distinguishable from other forms of the postgastrectomy syndrome. Gastric cancer tended to develop in these patients during the sixth decade of life, irrespective of when they had had their original gastric surgery, strongly suggesting an age-related factor. Although it would appear that previous gastric surgery for benign disease is not a major risk factor for the subsequent development of gastric cancer, such a relationship may exist. Patients who have undergone gastrectomy should be followed up carefully for the recurrence of symptoms.
回顾了1079例胃癌患者的记录。其中，只有21例（约2%）曾因良性疾病接受过胃部手术，通常是消化性溃疡。初次胃部手术与胃癌发现之间的平均间隔为26.9年。癌症表现的症状与胃切除术后综合征的其他形式无法区分。无论初次胃部手术的时间如何，这些患者的胃癌往往在生命的第六个十年发展，这强烈表明存在年龄相关因素。虽然既往因良性疾病进行胃部手术似乎不是随后发生胃癌的主要危险因素，但这种关系可能存在。接受过胃切除术的患者应密切随访症状复发情况。
