De Remigis P L, Damiani A, Cugini P, Halberg F, Sensi S, Scavo D
Boll Soc Ital Biol Sper. 1982 Feb;58(3-4):106-8.
We explored the circadian variation of core temperature, heart rate and blood pressure in hypothyroid and euthyroid male Sprague-Dawley rats. A circadian rhythm was quantified by the population mean-cosinor method for the core temperature of both hypothyroid and intact rats, whereas for the blood pressure and heart rate values a circadian rhythm was validated by rejection of the zero-amplitude assumption only in the hypothyroid rats. Whether hypothyroid rats adjust to new schedules at a rate different from euthyroid animals is an inference from these studies awaiting scrutiny.
我们研究了甲状腺功能减退和甲状腺功能正常的雄性Sprague-Dawley大鼠的核心体温、心率和血压的昼夜变化。采用群体均值-余弦分析法对甲状腺功能减退大鼠和正常大鼠的核心体温昼夜节律进行量化，而对于血压和心率值，仅在甲状腺功能减退大鼠中通过拒绝零振幅假设来验证昼夜节律。甲状腺功能减退大鼠是否以与甲状腺功能正常动物不同的速率适应新的时间表，是这些有待审查的研究得出的一个推断。
