水飞蓟宾对原代培养的乙醇中毒大鼠肝细胞脂质合成的影响。
The effect of silybin on lipid synthesis in ethanol-intoxicated rat hepatocytes in primary culture.
作者信息
Corazzi L, Arienti G, Tocchi L, Montanini I, Porcellati G
出版信息
Farmaco Sci. 1982 Feb;37(2):123-32.
PMID:7067807
Abstract
Rat liver cells in primary culture have been used to investigate the effects of ethanol and silybin on [2-3H]-glycerol incorporation into lipids. In these conditions, ethanol diminishes the incorporation of glycerol into lipids and modifies the labeling ratio: neutral lipid/phospholipid in favour of neutral lipid. 0.1 mM silybin can counteract this action of ethanol.
摘要
原代培养的大鼠肝细胞已被用于研究乙醇和水飞蓟宾对[2-³H]甘油掺入脂质的影响。在这些条件下，乙醇会减少甘油掺入脂质的量，并改变标记率：中性脂质/磷脂的比例有利于中性脂质。0.1 mM水飞蓟宾可以抵消乙醇的这种作用。
Zotero 插件