Kim Sue Kyung, Lee Eun-So
Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
Ann Dermatol. 2010 May;22(2):203-5. doi: 10.5021/ad.2010.22.2.203. Epub 2010 May 18.
Orofacial granulomatosis (OFG) is a term used to describe swelling of the orofacial area, mainly in the lips, secondary to an underlying granulomatous inflammatory process. OFG has been reported in association with systemic conditions such as sarcoidosis and Crohn's disease (CD). OFG may precede gastrointestinal disease, such as CD, by several years and may be the only obvious focus of the disease. Herein, we report a patient with OFG and non-symptomatic ulcerations of the ileocecal valve. The patient received intralesional triamcinolone injections every 2 weeks. After 6 weeks, all oral lesions showed marked improvement. The favourable treatment response of this patient suggests that intralesional triamcinolone can be used as a treatment option for patients with CD that have oral lesions. In addition, patients presenting with OFG should be carefully evaluated for gastrointestinal signs and symptoms.
口面部肉芽肿病（OFG）是一个用于描述口面部区域肿胀的术语，主要累及唇部，继发于潜在的肉芽肿性炎症过程。据报道，OFG与结节病和克罗恩病（CD）等全身性疾病有关。OFG可能比诸如CD之类的胃肠道疾病早数年出现，并且可能是该疾病唯一明显的病灶。在此，我们报告一例患有OFG和回盲瓣无症状溃疡的患者。该患者每2周接受一次病灶内注射曲安奈德治疗。6周后，所有口腔病变均显示出明显改善。该患者良好的治疗反应表明，病灶内注射曲安奈德可作为患有口腔病变的CD患者的一种治疗选择。此外，对于出现OFG的患者，应仔细评估其胃肠道症状和体征。
