Helbing G
Fortschr Med. 1982 Jan 21;100(3):83-7.
Viability and proliferative capacity of the chondrocytes are particularly important for a successful cartilage graft. This can be demonstrated by a new in vitro colony-forming assay. Only fetal or neonatal chondrocytes are considered to be applicable according to these criteria. Single cell suspensions prepared from articular cartilage can be transplanted without technical problems. In animal experiments articular cartilage regenerated after transplantation of neonatal chondrocytes, whereas only connective tissue was found in controls.
软骨细胞的活力和增殖能力对于成功的软骨移植尤为重要。这可以通过一种新的体外集落形成试验来证明。根据这些标准，仅胎儿或新生儿软骨细胞被认为是适用的。从关节软骨制备的单细胞悬液可以毫无技术问题地进行移植。在动物实验中，新生儿软骨细胞移植后关节软骨得以再生，而在对照组中仅发现结缔组织。
