Fainstein V, LeBlanc B, Weaver S, Bodey G P
Infection. 1982 Jan;10(1):50-2. doi: 10.1007/BF01640839.
The in vitro activity of thienamycin was compared to that of other antibiotics against a large panel of bacteria obtained in blood cultures from cancer patients. This compound was the most active against gram-positive cocci and also proved to be extremely active against the gram-negative bacteria. It was also very active against multi-resistant gram-negative bacilli. Because of its broad spectrum of activity including Pseudomonas spp., thienamycin deserves clinical testing in the future.
将硫霉素的体外活性与其他抗生素针对从癌症患者血培养物中分离出的大量细菌的活性进行了比较。该化合物对革兰氏阳性球菌活性最强，对革兰氏阴性菌也极具活性。它对多重耐药革兰氏阴性杆菌也非常有效。由于其包括假单胞菌属在内的广泛活性谱，硫霉素值得在未来进行临床试验。
