Shadomy S, May R S
Antimicrob Agents Chemother. 1981 Jan;19(1):201-4. doi: 10.1128/AAC.19.1.201.
N-Formimidoyl thienamycin (MK0787) was compared in vitro with three other beta-lactam and two aminoglycoside antibiotics. It was second in activity only to cefotaxime against members of the Enterobacteriaceae and to amikacin against Pseudomonas species. It was the most active antibiotic against Staphylococcus aureus. Resistance (minimal inhibitory concentration, greater than 128 microgram/ml) to N-formimidoyl thienamycin was not observed.
将N-甲脒硫霉素(MK0787)与其他三种β-内酰胺类抗生素和两种氨基糖苷类抗生素进行了体外比较。在抗肠杆菌科细菌方面,其活性仅次于头孢噻肟;在抗假单胞菌属方面,仅次于阿米卡星。它是对金黄色葡萄球菌活性最强的抗生素。未观察到对N-甲脒硫霉素的耐药性(最低抑菌浓度大于128微克/毫升)。