一种与核孔复合体边缘相关的大颗粒。
A large particle associated with the perimeter of the nuclear pore complex.
作者信息
Unwin P N, Milligan R A
出版信息
J Cell Biol. 1982 Apr;93(1):63-75. doi: 10.1083/jcb.93.1.63.
Abstract
The three-dimensional structure of the nuclear pore complex has been determined to a resolution of approximately 90 A by electron microscopy using nuclear envelopes from Xenopus oocytes. It is shown to be an assembly of several discrete constituents arranged with octagonal symmetry about a central axis. There are apparent twofold axes perpendicular to the octad axis which suggest that the framework of the pore complex is constructed from two equal but oppositely facing halves. The half facing the cytoplasm is in some instances decorated by large particles, similar in appearance and size to ribosomes.
摘要
利用非洲爪蟾卵母细胞的核被膜，通过电子显微镜已确定核孔复合体的三维结构分辨率约为90埃。结果表明，它是由几个离散的成分围绕中心轴呈八角对称排列而成的聚集体。有明显的垂直于八重轴的二重轴，这表明孔复合体的框架是由两个相等但相对的半部分构成的。面向细胞质的那一半在某些情况下会被大颗粒装饰，这些颗粒在外观和大小上与核糖体相似。
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