Oakley N, Rostron W
J R Soc Med. 1982 Apr;75(4):234-6. doi: 10.1177/014107688207500405.
Glycosylated haemoglobin (HbA), was measured in 164 Caucasian women aged 20-40 years who were using: (1) barrier contraceptive methods; (2) contraceptive pills with 30 micrograms ethinyloestradiol and 150 micrograms laevo-norgestrel; (3) contraceptive pills with 30-35 micrograms ethinyloestradiol and 0.5-1 mg norethisterone. Mean +/- 1 s.d. values for the three groups were 7.64 +/- 0.69, 7.56 +/- 0.56 and 7.27 +/- 0.74 respectively. Groups (1) and (2) did not differ significantly from one another but the mean value for group (3) was significantly lower than for the other groups (P less than 0.01). Age, percentage ideal body weight and smoking did not influence HbA, but the value was higher for parous than for nulliparous women (P = 0.02). These findings can be explained in terms of the known effects of oestrogens and progestogens on fasting blood glucose.
对164名年龄在20至40岁之间的白人女性进行了糖化血红蛋白（HbA）检测，这些女性分别采用：（1）屏障避孕法；（2）含30微克乙炔雌二醇和150微克左炔诺孕酮的避孕药；（3）含30 - 35微克乙炔雌二醇和0.5 - 1毫克炔诺酮的避孕药。三组的均值±1标准差分别为7.64±0.69、7.56±0.56和7.27±0.74。第（1）组和第（2）组之间无显著差异，但第（3）组的均值显著低于其他组（P＜0.01）。年龄、理想体重百分比和吸烟对HbA无影响，但经产妇的HbA值高于未产妇（P = 0.02）。这些发现可以根据已知的雌激素和孕激素对空腹血糖的影响来解释。
