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[多发性硬化症和重症肌无力中依赖胸腺的治疗性免疫抑制]

[Thymus-dependent therapeutic immunosuppression in multiple sclerosis and myasthenia].

作者信息

Lobzin V S, Golovkin V I

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(2):176-81.

PMID:7072415
Abstract

Fifty patients with myasthenia and disseminated sclerosis were treated by ultrasound and hydrocortisone applications to the thymus region. In the course of the treatment changes of rosette formation and the content of immunoglobulins and total complement in the serum were examined. A selective action of the local immunodepression on the T-system was revealed. The method is recommended for use in cases of contraindications to total immunodepressant therapy or to oral use of corticosteroids, as well as for treating outpatients.

摘要

五十例重症肌无力和播散性硬化症患者接受了胸腺区域的超声和氢化可的松治疗。在治疗过程中,检测了玫瑰花结形成的变化以及血清中免疫球蛋白和总补体的含量。结果显示局部免疫抑制对T系统具有选择性作用。该方法推荐用于全身免疫抑制疗法或口服皮质类固醇有禁忌证的病例,以及用于门诊患者的治疗。

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