Chaignon M, Aubert P, Martin M F, Lucsko M, Guedon J
Artif Organs. 1982 Feb;6(1):27-30. doi: 10.1111/j.1525-1594.1982.tb04053.x.
The hemodynamic effects (n = 8) of hemodialysis (HD) and hemofiltration (HF) were compared in the same group of dialyzed patients. The two procedures induced the same decrease in body weight, total blood volume, and blood pressure; however, hemodynamic alterations were different. Cardiac index and stroke index decreased markedly with HD and did not change significantly with HF, and peripheral resistance remained stable after HD and decreased significantly after HF. These results suggest that the maintenance of a high cardiac output may account for the lack of acute hypotensive episodes reported during HF. The reduction of blood pressure after HF is related to the decrease in total peripheral resistance. Thus, the arterial vasodilator effect induced by HF might explain the improvement of severe hypertension on long-term treatment with HF, as reported previously.
在同一组接受透析的患者中比较了血液透析（HD）和血液滤过（HF）的血流动力学效应（n = 8）。两种操作导致体重、总血容量和血压出现相同程度的下降；然而，血流动力学改变有所不同。心脏指数和每搏指数在血液透析时显著降低，而在血液滤过时无明显变化，外周阻力在血液透析后保持稳定，在血液滤过后显著降低。这些结果表明，维持高心输出量可能是血液滤过期间未报告急性低血压发作的原因。血液滤过后血压降低与总外周阻力降低有关。因此，如先前报道，血液滤过诱导的动脉血管舒张效应可能解释了长期血液滤过治疗重度高血压时的病情改善情况。
