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超滤在难治性充血性心力衰竭治疗中的应用

Ultrafiltration in the management of refractory congestive heart failure.

作者信息

Simpson I A, Rae A P, Simpson K, Gribben J, Boulton Jones J M, Allison M E, Hutton I

出版信息

Br Heart J. 1986 Apr;55(4):344-7. doi: 10.1136/hrt.55.4.344.

Abstract

Ultrafiltration was performed in nine patients with congestive cardiac failure that was refractory to conventional medical treatment. A mean of 12 X 7 litres of fluid was removed, and there was a sustained symptomatic improvement in all patients. Weight loss continued after ultrafiltration and a sustained increase in serum sodium concentration was also noted. A transient fall in right atrial pressure was seen only at four hours after ultrafiltration. No adverse haemodynamic effects were seen four and eighteen hours after fluid removal. Intracardiac dimensions measured by echocardiography remained unchanged. Ultrafiltration can be used to relieve symptoms in patients with refractory congestive heart failure and gross oedema.

摘要

对9例常规药物治疗无效的充血性心力衰竭患者进行了超滤治疗。平均清除了12×7升液体,所有患者的症状均持续改善。超滤后体重持续减轻,血清钠浓度也持续升高。仅在超滤后4小时观察到右心房压力短暂下降。液体清除后4小时和18小时未观察到不良血流动力学效应。超声心动图测量的心脏内尺寸保持不变。超滤可用于缓解难治性充血性心力衰竭和严重水肿患者的症状。

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Hemodynamic effects of hemodialysis and hemofiltration.血液透析和血液滤过的血流动力学效应。
Artif Organs. 1982 Feb;6(1):27-30. doi: 10.1111/j.1525-1594.1982.tb04053.x.
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Treatment of severe fluid overload by ultrafiltration.通过超滤治疗严重液体超负荷
N Engl J Med. 1974 Oct 10;291(15):747-51. doi: 10.1056/NEJM197410102911501.

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