Hanagasioglu M, Borbély A A
Behav Brain Res. 1982 Apr;4(4):359-68. doi: 10.1016/0166-4328(82)90060-2.
The effect of voluntary wheel-turning activity on sleep was investigated in the rat. In addition to scoring the conventional sleep states, a frequency analysis of the telemetrically recorded EEG-signal was performed to define a slow wave sleep (SWS) fraction of non-REM sleep (NREMS). The animals had access to the running-wheel during the first 3.5 days and the last 2.5 days of the 8-day recording period, but were prevented from entering the wheel in the 2 intervening days. Wheel-running (average distance run per day: 3015 m) occurred mainly during the dark-phase. The level of SWS was not significantly different for periods with access and without access to the wheel. The dark-time level of SWS relative to NREMS showed a trend towards higher values in the wheel-access period. The dark-time level of REM sleep was negatively correlated with the distance run in the wheel, and was lower in the access nights than in the no-access nights. Although locomotor activity produced some shifts in the sleep state distribution in the dark-phase, it had practically no effect on the rat's main daily sleep period in the light-phase.
在大鼠中研究了自愿转轮活动对睡眠的影响。除了对传统睡眠状态进行评分外，还对遥测记录的脑电图信号进行了频率分析，以确定非快速眼动睡眠（NREMS）中的慢波睡眠（SWS）比例。在8天记录期的前3.5天和最后2.5天，动物可以使用转轮，但在中间的2天被阻止进入转轮。转轮运动（每天平均跑步距离：3015米）主要发生在黑暗阶段。有转轮使用期和无转轮使用期的慢波睡眠水平无显著差异。相对于非快速眼动睡眠，慢波睡眠的黑暗期水平在有转轮使用期有升高趋势。快速眼动睡眠的黑暗期水平与转轮跑步距离呈负相关，有转轮使用的夜晚低于无转轮使用的夜晚。尽管运动活动在黑暗阶段导致了睡眠状态分布的一些变化，但实际上对大鼠在白天的主要睡眠时间没有影响。
