Haybittle J L, Blamey R W, Elston C W, Johnson J, Doyle P J, Campbell F C, Nicholson R I, Griffiths K
Br J Cancer. 1982 Mar;45(3):361-6. doi: 10.1038/bjc.1982.62.
From a multiple-regression analysis of prognostic factors and survival in a series of 387 patients with primary breast cancer, a prognostic index has been constructed, based on lymph-node stage, tumour size and pathological grade. This index is more discriminating than lymph-node stage alone, and enables a larger group of patients to be identified with a very poor prognosis.
通过对387例原发性乳腺癌患者的预后因素和生存情况进行多元回归分析,构建了一个基于淋巴结分期、肿瘤大小和病理分级的预后指数。该指数比单纯的淋巴结分期更具区分性,能够识别出更多预后极差的患者群体。